Publications

Transcranial direct current stimulation (tDCS) reduces motivation to drink ethanol and reacquisition of ethanol self‐administration in female mice. S Pedron, S Dumontoy, Mdc González‐Marín, F Coune, A Van Schuerbeek, E Haffen, M Naassila & V Van Waes. Accepté dans Scientific Reports.

Psilocybin targets a common molecular mechanism for cognitive impairment and increased craving in alcoholism.Meinhardt MW, Pfarr S, Fouquet G, …, Jeanblanc J,… Naassila M, Spanagel R, Sommer WH.Sci Adv. 2021 Nov 19;7(47):eabh2399. doi: 10.1126/sciadv.abh2399. pdf.

Astrogliosis and compensatory neurogenesis after the very first ethanol binge drinking-like exposures in adolescent rat C Vilpoux, G. Fouquet, C. Deschamps, E. Lefebvre, P. Gosset, J. Antol, L. Zabijak, I. Marcq, M. Naassila, O. Pierrefiche2021. Alcohol Clin Exp Res. Doi : 10.1111/acer.14757

[Clinical profile of elderly patients referred to liaison psychiatry for substance use disorders in an Academic Emergency Department]. Bonte-Baert A, Angerville B, Assal S, Dragos-Stan E, Naassila M, Dervaux A.Geriatr Psychol Neuropsychiatr Vieil. 2021. doi: 10.1684/pnv.2021.0977

Sugar a powerful substitute for ethanol in ethanol postdependent rats: evidence for clinical consideration. S Alaux-Cantin et al Addiction Biology 2021

The early impact of the COVID-19 lockdown on stress and addictive behaviours in an alcohol-consuming student population in France. Flaudias et al 2021 Frontiers in Psychiatry.

Sex difference in the vulnerability tio hippocampus plasticity impairment after binge-like ethanol exposure in adolescent rats: is estrogen the key? Rabiant et al Addiction Biology 2021

Component process analysis of verbal memory in a sample of students with a binge drinking pattern. Gierski et al 2020 Addictive Behaviors Reports

Interstrain differences in voluntary binge-like drinking behavior and in two acute ethanol injections-induced synaptic plasticity deficits in rats. Sauton P et al Addiction Biology 2020

Patch-clamp recording of LFS-induced long-term synaptic depression in rat hippocampus slices during early and late periods of neurodevelopment. Bertrand C et al Alcohol Clinical & Experimental Research.

Neural response to the implicit processing of emotional facial expression in binge drinking. S Lannoy, et al F Gierski, Alcohol & Alcoholism.

Training emotion regulation processes in alcohol-abstinent individuals: a pilot study. Nandrino JL et al Addictive Behaviors.

COVID-19 pandemic lockdown and problematic eating behaviors in a student population. V Flaudias, O Zerhouni, M Naassila, G Brousse, S Guillaume. Accepté dans J Behav Addictions.

Role of HSF2 in the NMDA-dependent neuroplasticity induced by chronic ethanol intake in mouse hippocampus; I Drissi, et al, O Pierrefiche. Addiction Biology.

Differential brain responses for perception of pain during empathic response in binge drinkers compared to non-binge drinkers. C L. Rae, F Gierski, K W. Smith, et al, M Naassila, T Duka. NeuroImage Clinical.

Vers une définition opérationnelle du binge drinking : une nécessité diagnostique et de recherche. P Maurage, et al, F Gierski, M Naassila.  Alcoologie & Addictologie.

Is self-compassion linked to treatment adherence in schizophrenia? L Uzer-Kremers et al. Schizophrenia Res.

What we talk about when we talk about binge drinking: Towards an integrated conceptualization and evaluation. P Maurage,et al Alcohol & Alcoholism 2020.

Sugar intake and craving during alcohol withdrawal in alcohol use disorder inpatients. Alarcon R, et al. Addict Biol. 2020.

Is R(+)-Baclofen the best option for the future of Baclofen in alcohol dependence pharmacotherapy? Insights from the preclinical side. Echeverry-Alzate V, Jeanblanc J, Sauton P, et al, Naassila M. Addict Biol. 2020 e12892.  PMID: 32146727

Disentangling the Relationship Between Self-Esteem and Problematic Alcohol Use Among College Students: Evidence From a Cluster Analytic Approach. Gierski F, et al, Naassila M, Quaglino V. Alcohol Alcohol. 2020;55(2):196-203. PMID:31845969

Vulnerability to ethanol sensitization predicts higher intake and motivation to self-administer ethanol: Proof of the incentive salience sensitization theory? González-Marín MDC, Coune F, Naassila M. Addict Biol. 2019.

Memory and plasticity impairment after binge drinking in adolescent rat hippocampus: GluN2A/GluN2B NMDA receptor subunits imbalance through HDAC2. Drissi I, Deschamps C, Fouquet G, Alary R, Peineau S, Gosset P, Sueur H, Marcq I, Debuysscher V, Naassila M, Vilpoux C, Pierrefiche O. Addict Biol. 2019 May 6:e12760. doi: 10.1111/adb.12760.

How could histone deacetylase activators be useful leads in the search for new therapeutics? Bourguet E, Naassila M. Future Med Chem. 2019

Methadone and buprenorphine treatments in patients with schizophrenia. Dervaux A et al. Schizophr Res. 2019

Substance-Use Disorders in Later Life. Angerville B, Naassila M, Dervaux A. N Engl J Med. 2019 Mar 21;380(12):1189. doi: 10.1056/NEJMc1900415.

Naassila M. Éditorial. Alcool : un impact sur la santé, même à faibles doses. Bull Epidemiol Hebd. 2019;(10-11):1767. http://invs.santepubliquefrance.fr/beh/2019/10-11/2019_10-11_0.html

Evaluation of N-acetylcysteine on ethanol self-administration in ethanol-dependent rats. Lebourgeois S, González-Marín MC, Antol J, Naassila M, Vilpoux C. Neuropharmacology. 2019 May 15;150:112-120. doi:10.1016/j.neuropharm.2019.03.010.

The Behavioral Economics of Alcohol Demand in French and American University Students. Martinetti MP et al. Alcohol Clin Exp Res. 2019

Disrupted Fear and Sadness Recognition in Binge Drinking: A Combined Group and Individual Analysis. Lannoy S, Benzerouk F, Maurage P, Barrière S, Billieux J, Naassila M, Kaladjian A, Gierski F. Alcohol Clin Exp Res. 2019.

Therapeutic Prospects of Cannabidiol for Alcohol Use Disorder and Alcohol-Related Damages on the Liver and the Brain. De Ternay J, Naassila M, et al , Rolland B. Front Pharmacol. 2019.   Free PMC Article

Intérêt de la N-acétylcystéine dans le traitement des addictions Isabelle Stoces, et al, M Naassila  Vol. 41 No 4, 2019 Alcoologie & Addictologie

Face validity of a pre-clinical model of operant binge drinking: just a question of speed. Jeanblanc J, et al. Addict Biol. 2019

Animal models of binge drinking, current challenges to improve face validity. Jeanblanc J, et al. Neurosci Biobehav Rev. 2019

La médecine de précision en addictologie. Un besoin médical non satisfait Mickael Naassila, Wim van den Brink 2018 Alcoologie & Addictologie

Article de synthèse de la 1ère journée nationale de recherche en alcoologie du 13 mars 2018 à Paris organisée par l'ITMO Neurosciences - INSERM - CNRS - AVIESAN

Ethanol-related behaviors in alpha-synuclein mutant mice and association of SNCA SNPs with anxiety in ethanol-dependent patients. Persyn W, Houchi H, Papillon CA, Martinetti M, Antol J, Guillaumont C, Dervaux A, Naassila M.  Alcohol Clin & Exp Res. pdf

Unexpected effect of cyclodepsipeptides bearing a sulfonylhydrazide moiety towards histone deacetylase activity. M Létévé, C Gonzalez, G Moroy, A Martinez, J Jeanblanc, R Legastelois, M Naassila, J Sapi, E Bourguet. Bioorganic Chemistry. pdf

Le binge drinking. Toujours aussi problématique et pas de solutions en vue, un peu de courage ! A&A  Vol. 40 No 1 (2018)

Evaluation of alcohol use disorders pharmacotherapies in a new preclinical model of binge drinking. MC González-Marín, S Lebourgeois, J Jeanblanc, M Diouf, and M Naassila. NEUROPHARMACOLOGY télécharger le pdf ici

Le binge drinking. Toujours aussi problématique et pas de solutions en vue, un peu de courage ! Mickaël Naassila. Alcoologie et Addictologie. 2018 ; 40 (1) : 3-5

La MATE-Fr. Introduction à la version française d’un instrument d’évaluation globale en addictologie. D Galland, N Simioni, G Schippers, T Broekman, S Alaux-Cantin, H Houchi, M Naassila, B Rolland. Alcoologie et Addictologie. 2018 ; 40 (2) : 140-148.

Non-invasive diagnosis of liver fibrosis in patients with alcohol-related liver disease by transient elastography: an individual patient data meta-analysis. Nguyen-Khac et al 6 july 2018.  The Lancet Gastroenterology & Hepatology

Interest of new alkylsulfonylhydrazide-type compound in the treatment of alcohol use disorders. Jeanblanc J, et al. Psychopharmacology (Berl). 2018

A placebo controlled trial of bezafibrate in primary biliary cholangitis. Corpechot C, ..., Nguyen-Khac E, et al. New England J Med. 2018. 378(23):2171-2181.

[Early detection and treatment of Alcohol dependence]. Dervaux A. Presse Med. 2018 Jun;47(6):532-534. doi: 10.1016/j.lpm.2018.05.012.

Synaptic plasticity modulation by circulating peptides and metaplasticity: Involvement in Alzheimer's disease. Peineau S, et al. Pharmacol Res. 2018

[Epidemiology of alcohol dependence]. Laqueille X, Lacombe M, Dervaux A. Presse Med. 2018 Jun;47(6):535-546. doi: 10.1016/j.lpm.2018.04.009.

[Psychiatric comorbidities of Alcohol dependence]. Dervaux A, Laqueille X. Presse Med. 2018 Jun;47(6):575-585. doi: 10.1016/j.lpm.2018.01.005.

Influence of comorbid alcohol use disorders on the clinical patterns of major depressive disorder: A general population-based study.Carton L, et al. Drug Alcohol Depend. 2018;

Neurobiological bases of alcohol addiction. Naassila M. Presse Med. 2018

Signaling lymphocytic activation molecules Slam and cancers: friends or foes? G Fouquet, I Marcq, V Debuysscher, J Bayry, AR Singh, A Bengrine, E Nguyen-Khac, M Naassila, H Bouhlal. Oncotarget 2018

Pharmacological activation of mGlu4 and mGlu7 receptors, by LSP2-9166, reduces ethanol consumption and relapse in rat. Lebourgeois S, Vilpoux C, Jeanblanc J, Acher F, Marie N,  Noble F, Naassila M. 2018 Neuropharmacol FI 5.012

GluN2B subunit of the NMDA receptor: the keystone of the effects of alcohol during neurodevelopmen. O Pierrefiche, M Naassila. 2018 Neurochem Res.Class I HDAC inhibitors: Potential new epigenetic therapeutics for alcohol use disorder (AUD). Bourguet E, Ozdarska K, Moroy G, Jeanblanc J & Naassila M. 2018 J Med Chem. IF 6.25

Effect of N-acetylcysteine on motivation, seeking and relapse to ethanol self-administration. Lebourgeois S, González-Marín María C, Jeanblanc J, Naassila M, Vilpoux C. Addict Biol. 2018 May 30. doi: 10.1111/adb.12521 FI 4.6

What place for prolonged-release buprenorphine depot-formulation Buvidal® in the treatment arsenal of opioid dependence? Insights from the French experience on buprenorphine.Vorspan F, et al. Expert Opin Drug Deliv. 2019

General principles of treatment in addictology. Laqueille X, et al. Rev Prat. 2018

Cannabis use disorders and psychiatric comorbidities. Dervaux A. Rev Prat. 2018

Can artificial intelligence be used for assessing a patient with alcohol dependence? Dervaux A. Presse Med. 2018

Early detection and treatment of Alcohol dependence. Dervaux A. Presse Med. 2018

1ère journée nationale de recherche en alcoologie 2018

Epidemiology of alcohol dependence. Laqueille X, et al. Presse Med. 2018

Psychiatric comorbidities of Alcohol dependence. Dervaux A, Laqueille X. Presse Med. 2018 PDF

Estimate of hepatocellular carcinoma incidence in patients with alcoholic cirrhosis. Ganne-Carrié N, et al; for CIRRAL Group. J Hepatol. 2018

Severe acute alcoholic hepatitis. Nguyen-Khac E, et al. Presse Med. 2018

Non-invasive diagnosis of liver fibrosis in patients with alcohol-related liver disease by transient elastography: an individual patient data meta-analysis. Nguyen-Khac E, et al. Lancet Gastroenterol Hepatol. 2018

Binge eating, but not other disordered eating symptoms, is a significant contributor of binge drinking severity: findings from a cross-sectional study among French students. B Rolland,  M Naassila,  C Duffau, H Houchi,  F Gierski and J André. Frontiers in Psychology 2017.

Long Term Depression in Rat Hippocampus and the Effect of Ethanol during Fetal Life. Pierrefiche O. Brain Sci. 2017 Nov 28;7(12).

Cloninger’s Temperament and Character Dimensions of Personality and Binge Drinking Among College Students. Gierski F, Benzerouk F, Duka T, Kaladjian A, Naassila M. 2017 Alcoholism & Clinical experimental research.

The Role of General Practitioners in the 2015 French Guidelines on Alcohol Misuse. B Rolland,  M Naassila,  F Paille,  H-J Aubin, On behalf of the Société Française d’Alcoologie. Alcohol and Alcoholism 2017, https://doi.org/10.1093/alcalc/agx054

Synaptoimmunology - roles in health and disease. Nisticò R, Salter E, Nicolas C, Feligioni M, Mango D, Bortolotto ZA, Gressens P, Collingridge GL, Peineau S. Mol Brain. 2017 10(1):26.

[Epigenetic mechanisms and alcohol use disorders: a potential therapeutic target]. Legastelois R, Jeanblanc J, Vilpoux C, Bourguet E, Naassila M. Biol Aujourdhui. 2017;211(1):83-91.

Comparison between the WHO and NIAAA criteria for binge drinking on drinking features and alcohol-related aftermaths: Results from a cross-sectional study among eight emergency wards in France. B Rolland et al. Drug and Alcohol Dependence · March 2017

Binge Drinking: Current Diagnostic and Therapeutic Issues. Rolland B, Naassila M. CNS Drugs. 2017. FI 4.9

Resistance to ethanol sensitization is associated with a loss of synaptic plasticity in the hippocampus. F. Coune, B. Silvestre de Ferron, MC Gonzalez-Marin, J. Antol, M Naassila, O. Pierrefiche. Synapse 2017 FI 2.12

Altered white matter integrity in whole brain and segments of corpus callosum, in young social drinkers with binge drinking pattern. KW. Smith, F Gierski, J Andre, NG. Dowell, M Cercignani, M Naassila, T Duka. 2017 Addiction Biology FI 4.6

Expertise collective INSERM "Les conduites addictives chez les adolescents". 2014. Vulnérabilité des adolescents aux addictions et corrélats neurobiologiques 159-186 Effets néfastes de l’alcool : impact du binge drinking sur le cerveau 187-215. M Naassila

Conduites d’alcoolisation et binge drinking chez l’adolescents : apport des neurosciences. Gierski, F. & Naassila, M. (2014). In Battaglia, N. & Gierski, F. (Eds.) (2014). L’addiction chez les adolescents : psychologie des conduites addictives. Paris : De Boeck - Solal (collection "Troubles du développement psychologique et des apprentissages) ; pages 17-60

Drogues et adolescence : un mauvais cocktail M NAASSILA. Textes et Documents pour la Classe (TDC) La revue des enseignants p 14-17

Memantine reduces alcohol drinking but not relapse in alcohol-dependent rats > S Alaux-Cantin, R Buttolo, H Houchi, J Jeanblanc & M Naassila  Addiction Biology 2014FI 5.9.

The histone deacetylase inhibitor sodium butyrate decreases excessive ethanol intake in dependent animals > E Simon O'Brien, S Alaux-Cantin, V Warnault, R Buttolo, M Naassila, C Vilpoux  Addiction Biology 2014FI 5.9.

Light alcohol intake during adolescence induces alcohol addiction in a neurodevelopmental model of schizophrenia > J Jeanblanc, K Balguerie, F Coune, RLegastelois, V Jeanblanc & M Naassila  Addiction Biology 2014FI 5.9.

Endogenous nitric oxide but not exogenous no-donor S-nitroprussiate facilitates NMDA excitation in spontaneous rhythmic neonatal rat brainstem slice > O Pierrefiche, M Naassila. Brain Research 2014 FI 2.88

Deciphering the relationship between vulnerability to ethanol-induced behavioral sensitization and ethanol consumption in outbred mice > R Legastelois, B Botia, F Coune, J Jeanblanc and M Naassila.  Addiction Biology 2013FI 5.9.

Hépatite alcoolique aiguë sévère. E. Nguyen-Khac, D. Chatelain, H. Houchi, V. Lloyd. EMC Hépatologie. 2014

Biture et cerveau, un mauvais cocktail > La Recherche; Addictions : Qui est menacé ? Peut-on s'en sortir ? dossiers n°6 octobre 2013

De nouvelles pistes contre l'alcoolisme > La Recherche; Addictions : Qui est menacé ? Peut-on s'en sortir ? dossiers n°6 octobre 2013

Neurobiologie de l’alcoolisme  > M. Naassila. Alcool et troubles mentaux. De la compréhension à la prise en charge du double diagnostic. Collection Médecine et psychothérapie. ELSEVIER MASSON

Chronic ethanol exposure during development: Disturbances of breathing and adaptation.  > C. Dubois , M. Kervern, M. Naassila, O. Pierrefiche. Respiratory Physiology & Neurobiology. FI 2.05

Human and Experimental Evidence Supporting a Role for Osteopontin in Alcoholic. Hepatitis. > O Morales-Ibanez, M Dominguez, S Ki, M Marcos, FJ. Chaves, E Nguyen-Khac, H Houchi, et al. Hepatology 2013 FI 11.7

BDNF mediates the suppression of alcohol self-administration by memantine > J Jeanblanc, F Coune, B Botia and M Naassila; Addiction Biology 2013 FI 5.9

Alcohol intoxications during adolescence increase motivation for alcohol in adult rats and induce neuroadaptations in the nucleus accumbens. >S Alaux-Cantin, V Warnault, R Legastelois, B Botia, O Pierrefiche, C Vilpoux & M Naassila Neuropharmacology 2013 FI 4.8

The adenosine A2A receptor agonist CGS 21680 decreases ethanol self-administration in both non-dependent and dependent animals > H Houchi, W Persyn, R Legastelois, M Naassila. Addiction Biology 2013FI 5.9.

Blockade of ethanol-induced behavioral sensitization by sodium butyrate: descriptive analysis of gene regulations in the striatum > B Botia, R Legastelois, , M Naassila. Alcohol Clin Exp Res. 2013FI 3.8

Expression of ethanol-induced behavioral sensitization is associated with alteration of chromatin remodeling in mice > B Botia, R Legastelois, M Naassila. PlosOne 2012 FI 4.0

Alcohol and rats. M Naassila. Elsevier Encyclopedia on Addictive behaviors, Biological Research on Addiction, Volume 2, 2013 > M Naassila. Elsevier Encyclopedia on Addictive behaviors, Biological Research on Addiction, Volume 2, 2013

Enjeux actuels et perspectives de la recherche sur l’addiction à l’alcool. M Naassila Le courrier des addictions Vol.14:n°3 (2012/07-08-09) – p. 15-17

Chronic and Intermittent Exposure to Alcohol Vapors A New Model of Alcohol-Induced Osteopenia in the Rat > D B. Maurel, C Jaffré, E Simon O’Brien, C C. Tournier,H Houchi, CL Benhamou, and M Naassila Alcohol Clin Exp Res. 2012 FI 3.4

Potential role of cortical 5-HT(2A) receptors in the anxiolytic action of cyamemazine in benzodiazepine withdrawal. > Benyamina A, Naassila M, Bourin M. Psychiatry Research 2012.

Glucocorticoids plus N-acetylcysteine in severe alcoholic hepatitis. > Nguyen-Khac E, Thevenot T, Piquet MA, Benferhat S, Goria O, Chatelain D, Tramier B, Dewaele F, Ghrib S, Rudler M, Carbonell N, Tossou H, Bental A, Bernard-Chabert B, Dupas JL; AAH-NAC Study Group. N Engl J Med. 2011 Nov 10;365(19):1781-9.IF 54.4

Fluoxetine, desipramine, and the dual antidepressant milnacipran reduce alcohol self-administration and/or relapse in dependent rats > E Simon O’Brien, R Legastelois, H Houchi, C Vilpoux, S Alaux-Cantin, O Pierrefiche, E André and M Naassila. Neuropsychopharmacology IF 6.99

Dépendances, regards croisés. Aspect clinique de l'addiction à l'alcool > M Naassila. Revue generale de droit medical.