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Université de Picardie Jules Verne
Groupe de recherche sur l'alcool et les pharmacodépendances

Publications du GRAP

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»Disentangling the Relationship Between Self-Esteem and Problematic Alcohol Use Among College Students: Evidence From a Cluster Analytic Approach. F Gierski,  F Benzerouk,  S Lannoy,  A Kaladjian, M Naassila et al.  Alcohol and Alcoholism 
»  Memory and plasticity impairment after binge drinking in adolescent rat hippocampus: GluN2A/GluN2B NMDA receptor subunits imbalance through HDAC2. Drissi I, Deschamps C, Fouquet G, Alary R, Peineau S, Gosset P, Sueur H, Marcq I, Debuysscher V, Naassila M, Vilpoux C, Pierrefiche O. Addict Biol. 2019 May 6:e12760. doi: 10.1111/adb.12760.

» Substance-Use Disorders in Later Life. Angerville B, Naassila M, Dervaux A. N Engl J Med. 2019 Mar 21;380(12):1189. doi: 10.1056/NEJMc1900415. 
»  Naassila M. Éditorial. Alcool : un impact sur la santé, même à faibles doses. Bull Epidemiol Hebd. 2019;(10-11):176-7.

» Evaluation of N-acetylcysteine on ethanol self-administration in ethanol-dependent rats. Lebourgeois S, González-Marín MC, Antol J, Naassila M, Vilpoux C. Neuropharmacology. 2019 May 15;150:112-120. doi:10.1016/j.neuropharm.2019.03.010.


La médecine de précision en addictologie. Un besoin médical non satisfait Mickael Naassila, Wim van den Brink 2018 Alcoologie & Addictologie
» Article de synthèse de la 1ère journée nationale de recherche en alcoologie du 13 mars 2018 à Paris organisée par l'ITMO Neurosciences - INSERM - CNRS - AVIESAN: pdf.
» Ethanol-related behaviors in alpha-synuclein mutant mice and association of SNCA SNPs with anxiety in ethanol-dependent patients. Persyn W, Houchi H, Papillon CA, Martinetti M, Antol J, Guillaumont C, Dervaux A, Naassila M.  Alcohol Clin & Exp Res. pdf
» Unexpected effect of cyclodepsipeptides bearing a sulfonylhydrazide moiety towards histone deacetylase activity. M Létévé, C Gonzalez, G Moroy, A Martinez, J Jeanblanc, R Legastelois, M Naassila, J Sapi, E Bourguet. Bioorganic Chemistrypdf
» Evaluation of alcohol use disorders pharmacotherapies in a new preclinical model of binge drinking. MC González-Marín, S Lebourgeois, J Jeanblanc, M Diouf, and M Naassila. NEUROPHARMACOLOGY télécharger le pdf ici
» Le binge drinking. Toujours aussi problématique et pas de solutions en vue, un peu de courage ! Mickaël Naassila. Alcoologie et Addictologie. 2018 ; 40 (1) : 3-5
» La MATE-Fr. Introduction à la version française d’un instrument d’évaluation globale en addictologie. D Galland, N Simioni, G Schippers, T Broekman, S Alaux-Cantin, H Houchi, M Naassila, B Rolland. Alcoologie et Addictologie. 2018 ; 40 (2) : 140-148.
» Non-invasive diagnosis of liver fibrosis in patients with alcohol-related liver disease by transient elastography: an individual patient data meta-analysis. Nguyen-Khac et al 6 july 2018.  The Lancet Gastroenterology & Hepatology
» A placebo controlled trial of bezafibrate in primary biliary cholangitis. Corpechot C, ..., Nguyen-Khac E, et al. New England J Med. 2018. 378(23):2171-2181.
»  Face validity of a preclinical model of operant binge drinking: Just a question of speed. Jeanblanc J, Sauton P, Jeanblanc V, Legastelois R, Echeverry-Alzate V, Lebourgeois S, Gonzalez-Marin MC, Naassila M. Accepté dans Addiction Biol 2018 FI 4.6
» [Early detection and treatment of Alcohol dependence]. Dervaux A. Presse Med. 2018 Jun;47(6):532-534. doi: 10.1016/j.lpm.2018.05.012.
» [Epidemiology of alcohol dependence]. Laqueille X, Lacombe M, Dervaux A. Presse Med. 2018 Jun;47(6):535-546. doi: 10.1016/j.lpm.2018.04.009.
» [Psychiatric comorbidities of Alcohol dependence]. Dervaux A, Laqueille X. Presse Med. 2018 Jun;47(6):575-585. doi: 10.1016/j.lpm.2018.01.005.
» Influence of comorbid alcohol use disorders on the clinical patterns of major depressive disorder: A general population-based study. L Carton⁠⁠, ⁠Philippe De Timary⁠, M Naassila⁠, et al B Rolland⁠ Drug & Alcohol Dep 2018
» Neurobiological bases of alcohol addiction. Naassila M. Presse Med. 2018
» Signaling lymphocytic activation molecules Slam and cancers: friends or foes? G Fouquet, I Marcq, V Debuysscher, J Bayry, AR Singh, A Bengrine, E Nguyen-Khac, M Naassila, H Bouhlal. Oncotarget 2018
» Pharmacological activation of mGlu4 and mGlu7 receptors, by LSP2-9166, reduces ethanol consumption and relapse in rat. Lebourgeois S, Vilpoux C, Jeanblanc J, Acher F, Marie N,  Noble F, Naassila M. 2018 Neuropharmacol FI 5.012
» GluN2B subunit of the NMDA receptor: the keystone of the effects of alcohol during neurodevelopmen. O Pierrefiche, M Naassila. 2018 Neurochem Res.
» Class I HDAC inhibitors: Potential new epigenetic therapeutics for alcohol use disorder (AUD). Bourguet E, Ozdarska K, Moroy G, Jeanblanc J & Naassila M. 2018 J Med Chem. IF 6.25
» Effect of N-acetylcysteine on motivation, seeking and relapse to ethanol self-administration. Lebourgeois S, González-Marín María C, Jeanblanc J, Naassila M, Vilpoux C. Addict Biol. 2018 May 30. doi: 10.1111/adb.12521 FI 4.6


» Binge eating, but not other disordered eating symptoms, is a significant contributor of binge drinking severity: findings from a cross-sectional study among French students. B Rolland,  M Naassila,  C Duffau, H Houchi,  F Gierski and J André. Frontiers in Psychology 2017.
» Long Term Depression in Rat Hippocampus and the Effect of Ethanol during Fetal Life. Pierrefiche O. Brain Sci. 2017 Nov 28;7(12). 
» Cloninger’s Temperament and Character Dimensions of Personality and Binge Drinking Among College Students. Gierski F, Benzerouk F, Duka T, Kaladjian A, Naassila M. 2017 Alcoholism & Clinical experimental research.
» The Role of General Practitioners in the 2015 French Guidelines on Alcohol Misuse. B Rolland,  M Naassila,  F Paille,  H-J Aubin, On behalf of the Société Française d’Alcoologie. Alcohol and Alcoholism 2017, 
» Synaptoimmunology - roles in health and disease. Nisticò R, Salter E, Nicolas C, Feligioni M, Mango D, Bortolotto ZA, Gressens P, Collingridge GL, Peineau S. Mol Brain. 2017 10(1):26.
» [Epigenetic mechanisms and alcohol use disorders: a potential therapeutic target]. Legastelois R, Jeanblanc J, Vilpoux C, Bourguet E, Naassila M. Biol Aujourdhui. 2017;211(1):83-91.
» Comparison between the WHO and NIAAA criteria for binge drinking on drinking features and alcohol-related aftermaths: Results from a cross-sectional study among eight emergency wards in France. B Rolland et al. Drug and Alcohol Dependence · March 2017
» Binge Drinking: Current Diagnostic and Therapeutic Issues. Rolland B, Naassila M. CNS Drugs. 2017. FI 4.9
» Resistance to ethanol sensitization is associated with a loss of synaptic plasticity in the hippocampus. F. Coune, B. Silvestre de Ferron, MC Gonzalez-Marin, J. Antol, M Naassila, O. Pierrefiche. Synapse 2017 FI 2.12
» Altered white matter integrity in whole brain and segments of corpus callosum, in young social drinkers with binge drinking pattern. KW. Smith, F Gierski, J Andre, NG. Dowell, M Cercignani, M Naassila, T Duka. 2017 Addiction Biology FI 4.6


» increase of KCC2 in hippocampal synaptic plasticity disturbances after perinatal ethanol exposure. B Silvestre de Ferron, C Vilpoux, M Kervern, A Robert, J Antol, M Naassila, O Pierrefiche. Addiction Biology 2016. FI 4.5
» Use of alcohol during pregnancy in France: another french paradox? O Pierrefiche, M Daoust, M Naassila J of Pregnancy & Child Health 2016 
» Hepatocyte SLAMF3 reduced specifically the multi-drugs resistance protein MRP-1 and increases HCC cells sensitization to anti-cancer drugs. G Fouquet, V Debuysscher, H Ouled-Haddou, M Simoes Eugenio, B Demey, A Rabbind Singh, C Ossart, M Al Bagami, JM Regimbeau, E Nguyen-Khac, M Naassila, I Marcq, H Bouhlal. Oncotarget FI 6.36
» Altered white matter integrity in whole brain and segments of corpus callosum, in young social drinkers with binge drinking pattern. KW. Smith, F Gierski, J Andre, NG. Dowell, M Cercignani, M Naassila, T Duka. 2015  Addiction Biology FI 5.4
» Comorbidity Between Psychiatric Diseases and Alcohol Use Disorders: Impact of Adolescent Alcohol Consumption. J Jeanblanc Current Addiction reports
» Sensitization to the Stimulant Motor Effects of Ethanol Is Not Dependent On Tolerance to Ataxic or Sedative Properties of Ethanol in Female Mice. R Legastelois, B Botia and M Naassila. Accepté dans J Alcohol Drug Depend 2015
» Two binges of ethanol a days keep the memory away in adolescent rats. B Silvestre de Ferron et al. 2015 Int J Neuropsychopharmacology FI 5.2
» Metacognitions about alcohol use among university students: Psychometric properties of the PAMS and NAMS French versions. Fabien Gierski, Marcantonio M Spada, Eveline Fois, Aurélie Picard, M Naassila, Martial Van der Linden. 2015 Drug and Alcohol Dependence FI 3.27.
» The Class I-specific HDAC inhibitor MS-275 decreases motivation to consume alcohol and relapse in heavy drinking rats. Jeanblanc J, Lemoine S, Jeanblanc V, Naassila M.Int J Neuropsychopharmacol. 2015. FI 5.2.
» Basal anxiety negatively correlates with vulnerability to ethanol-induced behavioral sensitization in DBA/2J mice: modulation by diazepam. Botia B, Legastelois R, Houchi H, Naassila M. Alcohol Clin Exp Res. 2015 Jan;39(1):45-54. FI 3.8.
» Aberrant NMDA-dependent LTD after perinatal ethanol exposure in young adult rat hippocampus . M Kervern, B Silvestre de Ferron, S Alaux-Cantin, O Fedorenko, J Antol, M Naassila, O Pierrefiche. Hippocampus 2015 FI 4.2.
» Effets de l'alcoolisation pendant la grossesse . H Houchi; O Pierrefiche, M Naassila, M Daoust. Les cahiers de nutrition et de diététique 2015
» Characterization of the deleterious effects induced by alcohol consumption in Binge-like drinking conditions in mice. H Lacaille, D Duterte-Boucher, D Liot, H Vaudry, M Naasila and D Vaudry. J Neurochem 2015FI 4.2.


» Expertise collective INSERM "Les conduites addictives chez les adolescents". 2014. Vulnérabilité des adolescents aux addictions et corrélats neurobiologiques 159-186 Effets néfastes de l’alcool : impact du binge drinking sur le cerveau 187-215. M Naassila
» Conduites d’alcoolisation et binge drinking chez l’adolescents : apport des neurosciences. Gierski, F. & Naassila, M. (2014). In Battaglia, N. & Gierski, F. (Eds.) (2014). L’addiction chez les adolescents : psychologie des conduites addictives. Paris : De Boeck - Solal (collection "Troubles du développement psychologique et des apprentissages) ; pages 17-60
» Drogues et adolescence : un mauvais cocktail M NAASSILA. Textes et Documents pour la Classe (TDC) La revue des enseignants p 14-17
» Memantine reduces alcohol drinking but not relapse in alcohol-dependent rats > S Alaux-Cantin, R Buttolo, H Houchi, J Jeanblanc & M Naassila  Addiction Biology 2014FI 5.9.
» The histone deacetylase inhibitor sodium butyrate decreases excessive ethanol intake in dependent animals > E Simon O'Brien, S Alaux-Cantin, V Warnault, R Buttolo, M Naassila, C Vilpoux  Addiction Biology 2014FI 5.9.
» Light alcohol intake during adolescence induces alcohol addiction in a neurodevelopmental model of schizophrenia > J Jeanblanc, K Balguerie, F Coune, RLegastelois, V Jeanblanc & M Naassila  Addiction Biology 2014FI 5.9.
» Endogenous nitric oxide but not exogenous no-donor S-nitroprussiate facilitates NMDA excitation in spontaneous rhythmic neonatal rat brainstem slice > O Pierrefiche, M Naassila. Brain Research 2014 FI 2.88
» Deciphering the relationship between vulnerability to ethanol-induced behavioral sensitization and ethanol consumption in outbred mice > R Legastelois, B Botia, F Coune, J Jeanblanc and M Naassila.  Addiction Biology 2013FI 5.9.
» Hépatite alcoolique aiguë sévère. E. Nguyen-Khac, D. Chatelain, H. Houchi, V. Lloyd. EMC Hépatologie. 2014
» Biture et cerveau, un mauvais cocktail > La Recherche; Addictions : Qui est menacé ? Peut-on s'en sortir ? dossiers n°6 octobre 2013
» De nouvelles pistes contre l'alcoolisme > La Recherche; Addictions : Qui est menacé ? Peut-on s'en sortir ? dossiers n°6 octobre 2013
» Neurobiologie de l’alcoolisme  > M. Naassila. Alcool et troubles mentaux. De la compréhension à la prise en charge du double diagnostic. Collection Médecine et psychothérapie. ELSEVIER MASSON
» Chronic ethanol exposure during development: Disturbances of breathing and adaptation.  > C. Dubois , M. Kervern, M. Naassila, O. Pierrefiche. Respiratory Physiology & Neurobiology. FI 2.05
» Human and Experimental Evidence Supporting a Role for Osteopontin in Alcoholic. Hepatitis. > O Morales-Ibanez, M Dominguez, S Ki, M Marcos, FJ. Chaves, E Nguyen-Khac, H Houchi, et al. Hepatology 2013 FI 11.7
» BDNF mediates the suppression of alcohol self-administration by memantine > J Jeanblanc, F Coune, B Botia and M Naassila; Addiction Biology 2013 FI 5.9
» Alcohol intoxications during adolescence increase motivation for alcohol in adult rats and induce neuroadaptations in the nucleus accumbens. >S Alaux-Cantin, V Warnault, R Legastelois, B Botia, O Pierrefiche, C Vilpoux & M Naassila Neuropharmacology 2013 FI 4.8
» The adenosine A2A receptor agonist CGS 21680 decreases ethanol self-administration in both non-dependent and dependent animals > H Houchi, W Persyn, R Legastelois, M Naassila. Addiction Biology 2013FI 5.9.
» Blockade of ethanol-induced behavioral sensitization by sodium butyrate: descriptive analysis of gene regulations in the striatum > B Botia, R Legastelois, , M Naassila. Alcohol Clin Exp Res. 2013FI 3.8


» Expression of ethanol-induced behavioral sensitization is associated with alteration of chromatin remodeling in mice > B Botia, R Legastelois, M Naassila. PlosOne 2012 FI 4.0
» Alcohol and rats. M Naassila. Elsevier Encyclopedia on Addictive behaviors, Biological Research on Addiction, Volume 2, 2013 > M Naassila. Elsevier Encyclopedia on Addictive behaviors, Biological Research on Addiction, Volume 2, 2013
» Enjeux actuels et perspectives de la recherche sur l’addiction à l’alcool. M Naassila Le courrier des addictions Vol.14:n°3 (2012/07-08-09) – p. 15-17
» Chronic and Intermittent Exposure to Alcohol Vapors A New Model of Alcohol-Induced Osteopenia in the Rat > D B. Maurel, C Jaffré, E Simon O’Brien, C C. Tournier,H Houchi, CL Benhamou, and M Naassila Alcohol Clin Exp Res. 2012 FI 3.4
» Potential role of cortical 5-HT(2A) receptors in the anxiolytic action of cyamemazine in benzodiazepine withdrawal. > Benyamina A, Naassila M, Bourin M. Psychiatry Research 2012.
» Glucocorticoids plus N-acetylcysteine in severe alcoholic hepatitis. > Nguyen-Khac E, Thevenot T, Piquet MA, Benferhat S, Goria O, Chatelain D, Tramier B, Dewaele F, Ghrib S, Rudler M, Carbonell N, Tossou H, Bental A, Bernard-Chabert B, Dupas JL; AAH-NAC Study Group. N Engl J Med. 2011 Nov 10;365(19):1781-9.IF 54.4
» Fluoxetine, desipramine, and the dual antidepressant milnacipran reduce alcohol self-administration and/or relapse in dependent rats > E Simon O’Brien, R Legastelois, H Houchi, C Vilpoux, S Alaux-Cantin, O Pierrefiche, E André and M Naassila. Neuropsychopharmacology IF 6.99
» Dépendances, regards croisés. Aspect clinique de l'addiction à l'alcool > M Naassila. Revue generale de droit medical.


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